What is the meaning of Corticomedullary differentiation?
Corticomedullary differentiation (CMD) abnormality (absent/reversed) is a parameter that can indicate possible nephropathy. The evolution of CMD across gestation had not been well established. Devrendt et al demonstrated the presence of CMD in all fetuses older then 20 weeks.
What causes poor Corticomedullary differentiation?
Loss of CMD has been observed in renal insufficiency, secondary to a variety of etiologies, including glomerulonephritis, acute tubular necrosis, end-stage chronic renal failure, obstructive hydronephrosis, Fabry’s disease, and acute allograft rejection (1-8).
What is poor CMD in kidney?
easily visualized corticomedullary differentiation (CMD). Loss of CMD has been observed in renal insufficiency secondary to a variety of etiologies, such as glomerulonephritis, acute tubular necrosis, end-stage chronic renal failure, obstructive hydronephrosis, and acute allograft rejection (1-3).
What is CMD in USG?
Cortico-medullary differentiation (CMD; determined by the different tissue characteristics of the cortex and medulla) is a well-established characteristic of renal sonography in neonates and young children.
What is Corticomedullary cyst?
These cysts impair kidney function, initially causing increased urine production (polyuria), excessive thirst (polydipsia), general weakness, and extreme tiredness (fatigue). Nephronophthisis leads to end-stage renal disease (ESRD) later in childhood or in adolescence.
Is loss of CMD in kidney curable?
There is no cure for chronic kidney disease.
What is CMD in ultrasound?
Cortico-medullary differentiation (CMD; determined by the different tissue characteristics of the cortex and medulla) is a well-established characteristic of renal sonography in neonates and young children. The CMD can be visualized already around 18–20 weeks’ gestation.
What is normal kidney size?
Normally, kidneys are about the size of a fist or 10 to 12 cm (about 5 inches). Kidney atrophy means that the kidney is smaller than normal. This can happen for two basic reasons.
What causes medullary cystic kidney disease?
Medullary cystic kidney disease is caused by changes in the MUC1 gene. This gene provides instructions for making a protein called mucin 1. Changes in the gene lead to the production of an altered mucin protein. It is not known how this change causes MCKD.
What is acquired renal cystic disease?
Acquired cystic kidney disease happens when a person’s kidneys develop fluid-filled sacs, called cysts, over time. Acquired cystic kidney disease is not the same as polycystic kidney disease (PKD), another disease that causes the kidneys to develop multiple cysts.