What is TAILORx?

What is TAILORx?

TAILORx is one of the first trials to examine a methodology for personalizing cancer treatment. The study has randomized more than 10,200 women with this type of breast cancer at 1,182 sites in the United States, Australia, Canada, Ireland, New Zealand, and Peru.

What is a good Oncotype score?

A score between 21 and 25 means you have a medium risk of the cancer returning if you get hormone treatment. The benefits of chemotherapy may outweigh the risk of side effects. A score between 26 and 100 means you have a higher risk that the disease might come back.

Is a low Oncotype score good?

Research Confirms Women With Oncotype DX Recurrence Score of 11 or Lower Can Skip Chemotherapy. The prospective PlanB study has found that women with a Recurrence Score of 11 or lower who skipped chemotherapy based on the Recurrence Score had excellent 5-year survival rates.

What is the average Oncotype DX score?

The mean Oncotype Dx score was 17.0 ± 9.1; it was 14.1 ± 6.8 for Grade-I tumors; 15.7 ± 7.5 for grade -II tumors; and 23.2 ± 12.3 for grade-III tumors [Mean Oncotype Dx score across Tumor grades was compared by ANOVA (η = 0.121), p < 0.001].

What is Nsabp b20?

Abstract. Background: The B-20 study of the National Surgical Adjuvant Breast and Bowel Project (NSABP) was conducted to determine whether chemotherapy plus tamoxifen would be of greater benefit than tamoxifen alone in the treatment of patients with axillary lymph node-negative, estrogen receptor-positive breast cancer …

What does Oncotype score of 17 mean?

Recurrence Score of 0-15: The cancer has a low risk of recurrence. The benefits of chemotherapy likely will not outweigh the risks of side effects. Recurrence Score of 16-20: The cancer has a low to medium risk of recurrence.

What determines if you need chemotherapy?

Your doctor might suggest chemotherapy if there is a chance that your cancer might spread in the future. Or if it has already spread. Sometimes cancer cells break away from a tumour. They may travel to other parts of the body through the bloodstream or lymphatic system.

Has anyone had recurrence with low Oncotype?

There is a predicted recurrence rate of 6.8% at 10 years with an RS of less than 18, considered low, with the use of hormonal treatment alone.

What is the Oncotype DX test?

The Oncotype DX is a test that may predict how likely it is that your breast cancer will return. It also predicts whether you will benefit from having chemotherapy in addition to hormone therapy. The test results can help you and your doctors make a treatment plan that’s right for you.

Begin typing your search term above and press enter to search. Press ESC to cancel.

Back To Top