What is hypertrophic Pachymeningitis?

What is hypertrophic Pachymeningitis?

Hypertrophic Pachymeningitis (HP) denotes inflammation and thickening of the dura mater that can be idiopathic or secondary to a wide variety of conditions. Clinically, HP can present as debilitating headaches and cranial nerve defects but in other cases may be completely asymptomatic.

What causes hypertrophic Pachymeningitis?

HP is a rare chronic fibrosing inflammatory process that involves the cerebral and/or spinal dura mater. Causes include vascular abnormality, trauma, infection, neoplasm, and neuro-inflammatory conditions. IHP is diagnosed if no cause can be identified.

What is Pachymeningitis?

Pachymeningitis is a rare illness which can be shown by magnetic resonance imaging (MRI) to be a thickening of the intracranial dura mater, when associated with an infectious, malignant, or rheumatic systematic disease.1–,6 “Idiopathic hypertrophic cranial pachymeningitis” is also noticeable, and is based on a process …

Is Pachymeningitis curable?

Previous reports found a favorable response of IgG4-RP to steroids, suggesting that this disease is benign and treatable. However, the long-term treatment response and clinical course remain unknown.

How is Pachymeningitis diagnosed?

Magnetic resonance imaging (MRI) is essential for the diagnosis. T1-weighted images shows isointense meningeal thickening with contrast enhancement and T2-weighted images demonstrates hypointense lesions (4).

What causes thickening of dura mater?

Since then, a number of factors have been found that can lead to inflammatory thickening of the dura mater, including other infections (fungal infection), systemic autoimmune diseases (rheumatoid arthritis, Wegener’s granulomatosis), neurosarcoidosis and neoplasms (2, 3) (Fig. 3).

How do you say Pachymeningitis?

  1. Phonetic spelling of pachymeningitis. pachy-menin-gi-tis. păk′ē-mĕn′ĭn-jī′tĭs.
  2. Meanings for pachymeningitis.
  3. Translations of pachymeningitis. French : pachyméningite. Italian : pachimeningite.

What is inflammation of the dura?

Pachymeningitis is a rare inflammatory disorder that leads to thickening of the dura mater, the outermost of three layers forming the meninges, which provide protection and support to the brain and spinal cord.

What does dural thickening mean?

Hypertrophic pachymeningitis is a rare form of diffuse inflammatory disease that causes thickening of the dura mater. It can involve the cranial or the spinal dura or both.

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