What defines thyroid storm?
Thyroid storm, also referred to as thyrotoxic crisis, is an acute, life-threatening, hypermetabolic state induced by excessive release of thyroid hormones (THs) in individuals with thyrotoxicosis. Thyroid storm may be the initial presentation of thyrotoxicosis in undiagnosed children, particularly in neonates.
What labs indicate thyroid storm?
Although no lab test is absolutely confirmatory for thyroid storm, the pattern of low TSH and elevated T3/T4 suggests hyperthyroidism and compliments the clinical manifestations of thyroid storm described.
What is the difference between thyroid storm and thyrotoxicosis?
Thyrotoxicosis is a common endocrine condition that may be secondary to a number of underlying processes. Thyroid storm (also known as thyroid or thyrotoxic crisis) represents the severe end of the spectrum of thyrotoxicosis and is characterized by compromised organ function.
How do you treat thyroid storm?
High-dose propylthiouracil (PTU) or methimazole may be used for treatment of thyroid storm. PTU has a theoretical advantage in severe thyroid storm because of its early onset of action and capacity to inhibit peripheral conversion of T4 to T3.
What is thyroid storm after thyroidectomy?
Thyroid storm, also referred to as thyrotoxic crisis, is an acute, life-threatening, hypermetabolic state induced by excessive release of thyroid hormones (THs) in individuals with thyrotoxicosis.
Can you have a thyroid storm if you have hypothyroidism?
The decompensated, severe forms of hypothyroidism and hyperthyroidism, termed myxedema coma and thyroid storm, are associated with increased morbidity and mortality. Prompt recognition of both conditions is necessary to initiate treatment and supportive measures.
Which of the following distinguishes hyperthyroidism from thyroid storm?
One major sign of thyroid storm that differentiates it from oridnary hyperthyroidism is a marked elevation of body temperature, which may be as high as 105-106 F (40.5-41.1 C). Thyroid storm is unusual, but is a life-threatening emergency when it does occur.
What can precipitate a thyroid storm?
Thyroid storm may be precipitated by a number of factors including intercurrent illness, especially infections (Table 1). Pneumonia, upper respiratory tract infection, enteric infections, or any other infection can precipitate thyroid storm.