What are the components of paracetamol?
Each tablet contains 500mg of paracetamol. The other ingredients are, maize starch, potassium sorbate, purified talc, stearic acid, povidone, and soluble starch.
What is the pharmacokinetics of paracetamol?
Paracetamol is readily absorbed from the gastrointestinal tract with peak plasma concentrations occurring about 30 minutes to 2 hours after ingestion. It is metabolised in the liver (90-95%) and excreted in the urine mainly as the glucuronide and sulphate conjugates. Less than 5% is excreted as unchanged paracetamol.
What is the pharmacodynamics of paracetamol?
Pharmacodynamics/Mechanism of action: Paracetamol is a p-aminophenol derivative that exhibits analgesic and antipyretic activity. It does not possess anti-inflammatory activity. Paracetamol is thought to produce analgesia through a central inhibition of prostaglandin synthesis.
What is the physical appearance of paracetamol?
COLOURLESS CRYSTALS OR CRYSTALLINE POWDER. Explosive limits, vol% in air: 15 -? A nuisance-causing concentration of airborne particles can be reached quickly. Ingestion may cause effects on the kidneys and liver.
What is pharmacodynamics of paracetamol?
What is paracetamol?
What is paracetamol? Paracetamol (acetaminophen) is a pain reliever and a fever reducer. The exact mechanism of action of is not known. Paracetamol is used to treat many conditions such as headache, muscle aches, arthritis, backache, toothaches, colds, and fevers.
What are the uses of white uncoated paracetamol?
White uncoated tablets. Paracetamol has analgesic and antipyretic actions similar to those of aspirin and hence is a suitable alternative for patients sensitive to aspirin. 1) For the relief of mild to moderate pain and febrile conditions, eg headache, toothache, colds, influenza, rheumatic pain and dysmenorrhoea.
What is the sodium content of paracetamol?
This medicinal product contains less than 1 mmol sodium (23 mg) per each tablet, that is to say essentially ‘sodium-free’. The speed of absorption of Paracetamol may be increased by metoclopramide or domperidone and absorption reduced by colestyramine.
What is the packaging for paracetamol tablets?
Paracetamol Tablets are packaged in to blister packs containing 10 tablets. The blister packs are constructed of clear,transparent PVC (0.25mm ) backed up with child resistant push through foil ( 20 micron aluminium foil /15 micron PVC film )