What is ovarian folliculogenesis?
Folliculogenesis is the developmental process of ovarian follicles starting from a reserve of quiescent primordial follicles set up in early life and ending with either ovulation or follicular death by atresia.
How long does early folliculogenesis last?
Folliculogenesis lasts for approximately 375 days. It coincides with thirteen menstrual cycles. The process begins continuously, meaning that at any time the ovary contains follicles in all stages of development, and ends when a mature oocyte departs from the preovulatory follicle in a process called ovulation.
Does folliculogenesis start puberty?
At puberty, clutches of follicles begin folliculogenesis, entering a growth pattern that ends in ovulation (the process where the oocyte leaves the follicle) or in atresia (death of the follicle’s granulosa cells).
What are the stages of follicle development?
Preantral follicular development can be divided into three stages: activation of primordial follicles, the primary to secondary follicle transition, and the development of secondary follicles to the periantral stage.
What causes folliculogenesis?
The process of folliculogenesis occurs within the cortex of the ovary (Fig. 2). Folliculogenesis can be regarded as a process of attaining successively higher levels of organization by means of cell proliferation and cytodifferentiation.
What is the outcome of the process of folliculogenesis?
Folliculogenesis is the process in which a recruited primordial follicle grows and develops into a specialized graafian follicle with the potential to either ovulate its egg into the oviduct at mid-cycle to be fertilized or to die by atresia.
What triggers folliculogenesis?
Specialized hypothalamic neurons secrete pulses of gonadotropin-releasing hormone (GnRH) into the portal blood vessels, which acts on the gonadotrophs to cause a pulsatile release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which act on ovarian follicle cells to control folliculogenesis.
What triggers Folliculogenesis?
What hormones are involved in Folliculogenesis?
Although GnRH, FSH, and LH are critically important in regulating folliculogenesis, hormones and growth factors, which are themselves products of the follicle, can act locally to modulate (amplify or attenuate) FSH and LH action.
What is a good size follicle for fertilization?
When your follicles have reached around 18-20mm in diameter they are deemed ready for egg collection.