What is Haemate?
Haemate P/Humate-P is an intermediate-purity VWF/FVIII concentrate with extensive clinical experience in VWD. This concentrate has been shown to correct haemostatic defects of VWD, with efficacy ratings of good/excellent in nearly all patients treated for bleeding or surgical events.
How do you administer Humate-P?
Do not refrigerate Humate-P after reconstitution. Administer within 3 hours after reconstitution. Slowly infuse the solution (maximally 4 mL/minute) with a suitable intravenous administration set. Discard the administration equipment and any unused Humate-P after use.
How does desmopressin work in hemophilia?
Desmopressin (DDAVP®) is used to help stop bleeding in patients with von Willebrand’s disease or mild hemophilia A. DDAVP causes the release of von Willebrand’s antigen from the platelets and the cells that line the blood vessels where it is stored. Von Willebrand’s antigen is the protein that carries factor VIII.
Is Humate-P A blood product?
HUMATE-P is made from human blood and could contain infectious agents. The risk that these agents may transmit disease cannot be completely eliminated, but has been reduced by screening plasma donors and testing donated plasma for certain viruses, and by inactivating and/or removing viruses during manufacturing.
How long is Humate-P infusion?
Do not use visibly cloudy solutions or solutions still containing flakes or particles after filtration. Do not refrigerate HUMATE-P after reconstitution. Administer within 3 hours after reconstitution. Slowly infuse the solution (maximally 4 mL/minute) with a suitable intravenous administration set.
How long is Humate-P good for?
Before reconstitution, HUMATE-P can be safely stored at room temperature (25°C [77°F]) for up to 36 months. (After reconstitution, HUMATE-P should be used within 3 hours.)
How is Humate-P supplied?
Dosage Forms and Strengths Humate-P is available as a sterile, lyophilized powder for intravenous administration following reconstitution. Each single-dose vial of Humate-P contains the labeled amount of VWF:RCo and FVIII activity expressed in International Units (IU).
How safe is desmopressin?
Treatment with intranasal and oral formulations of desmopressin is generally well tolerated, and side effects are usually minor. The risk of hyponatraemia, although small, can be reduced by adhering to the indications, dosing recommendations and precautions when prescribing desmopressin.
What are the side effects of desmopressin?
Common side effects of DDAVP include:
- upset stomach or stomach pain,
- diarrhea, or.
- flushing of the face (warmth, redness, tingly feeling).