What class of drug is Perjeta?
This medication is classified as an “antineoplastic agent and a monoclonal antibody”.
What is the generic name for Perjeta?
Perjeta™ is the trade name for the generic drug Pertuzumab. In some cases, health care professionals may use the generic name Pertuzumab when referring to the trade drug name Perjeta™. Drug Type: Perjeta™ is an anti-cancer (“antineoplastic” or “cytotoxic”) chemotherapy drug.
What type of drugs are Herceptin and Perjeta?
Both Herceptin and Perjeta are HER2 inhibitors. They work against HER2-positive breast cancer by blocking the chemical signals that tell the cancer cells to grow. Traditionally, Herceptin and Perjeta are given intravenously, which means they’re delivered directly into your bloodstream through an IV or a port.
What is the drug Perjeta used for?
PERJETA® (pertuzumab) is a prescription medicine approved for use in combination with Herceptin® (trastuzumab) and docetaxel in people who have HER2-positive breast cancer that has spread to different parts of the body (metastatic) and who have not received anti-HER2 therapy or chemotherapy for metastatic breast cancer …
Is Perjeta an immunotherapy drug?
By blocking the signals, Perjeta can slow or stop the growth of the breast cancer. Perjeta and Herceptin are examples of immune targeted therapy. In addition to blocking HER2 receptors, Perjeta can also help fight breast cancer by alerting the immune system to destroy cancer cells onto which it is attached.
Which is stronger Taxol or Taxotere?
According to an article recently published in the Annals of Oncology, longer follow-up results indicate that the chemotherapy agent Taxotere® (docetaxel) remains superior to the chemotherapy agent Taxol® (paclitaxel) in the treatment of metastatic breast cancer among patients who have received prior therapy with …
Will my hair grow back after Taxotere?
Usually, this harm is temporary, with many patients having their hair return within several months. As long as the hair follicles have not been permanently destroyed by Taxotere, the hair should regrow. But up to about 6% of Taxotere patients have permanent hair follicle damage.
Will I lose my hair with PERJETA?
Hair thinning or hair loss Pertuzumab and trastuzumab do not usually cause people to lose their hair. Any hair loss caused by chemotherapy should be temporary and in most cases your hair will begin to grow back once your chemotherapy has ended.
What is the sister drug to Taxol?
Abraxane (chemical name: albumin-bound or nab-paclitaxel) is a different form of paclitaxel than Taxol (chemical name: paclitaxel). Both medicines are taxanes, a powerful type of chemotherapy medicine that can stop cancer cells from repairing themselves and making new cells.
Does pubic hair grow back after chemotherapy?
Hair loss typically starts one to three weeks after chemotherapy is started. The hairs on the scalp fall out first, and then a little later facial hair, body hair and pubic hair may fall out too. A few weeks after the end of chemotherapy, the hairs start to grow back in most people.
Is Perjeta a chemotherapy drug?
Perjeta (pertuzumab) is considered a targeted cancer therapy, which is different from chemotherapy. Chemotherapy kills cancer cells that grow rapidly, but may also affect normal cells. Targeted drug therapy like Perjeta attacks HER2 proteins on certain cancer cells that cause rapid growth.
What are the side effects of Perjeta for breast cancer?
The most common side effects of PERJETA when given with Herceptin and chemotherapy as part of an early breast cancer regimen after surgery are: 1 Diarrhea 2 Nausea 3 Hair Loss 4 Feeling tired 5 Damage to the nerves (numbness, tingling, pain in hands/feet) 6 Vomiting
What is the recommended dose of Perjeta?
Recommended Doses And Schedules. The initial dose of PERJETA is 840 mg administered as a 60-minute intravenous infusion, followed every 3 weeks by a dose of 420 mg administered as an intravenous infusion over 30 to 60 minutes.
What should I do if I have side effects from Perjeta?
You are encouraged to report side effects to Genentech and the FDA. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at 1-888-835-2555. Talk to a healthcare professional for more information about the benefits and risks of PERJETA.