How do you administer linezolid IV?
How should this medicine be used? Linezolid injection comes as a solution (liquid) to be infused into a vein. It is usually given as an intravenous infusion over 30 minutes to two hours twice a day (every 12 hours) for 10 to 28 days.
How is linezolid IV supplied?
ZYVOX I.V. Injection is supplied in single-dose, ready-to-use infusion bags. Parenteral drug products should be inspected visually for particulate matter prior to administration. Check for minute leaks by firmly squeezing the bag.
Why linezolid is covered?
Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA)….Linezolid.
| Clinical data | |
|---|---|
| Bioavailability | ~100% (oral) |
| Protein binding | Low (31%) |
| Metabolism | liver (50–70%, CYP not involved) |
How is linezolid taken?
Linezolid comes as a tablet and oral suspension (liquid) to take by mouth. It is usually taken with or without food twice a day (every 12 hours) for 10 to 28 days. Children 11 years of age and younger usually take linezolid with or without food two to three times a day (every 8 to 12 hours) for 10 to 28 days.
What should I monitor with linezolid?
Monitoring parameters include heart rate, blood pressure, blood glucose, weekly complete blood count (CBC), and visual function. Blood pressure requires close monitoring in patients with untreated hyperthyroidism.
Can you crush linezolid?
The pharmacokinetics and tolerance of linezolid administered orally or intravenously were analysed. Linezolid was administered intravenously at a dosage of 10 mg/kg every 8 h and then orally. In oral administration, 10 mg/kg or 15 mg/kg was given every 8 h as a powder made by crushing tablets.
How is Zyvox administered?
ZYVOX I.V. Injection should be administered by intravenous infusion over a period of 30 to 120 minutes. Do not use this intravenous infusion bag in series connections. Additives should not be introduced into this solution.
What is linezolid IV?
Linezolid injection is used to treat certain bacterial infections in many different parts of the body, including certain types of skin infections or pneumonia. Linezolid belongs to the family of medicines called antibiotics. It works by killing bacteria or preventing their growth.
How do you mix linezolid?
The liquid form of linezolid should be gently mixed by turning the bottle upside down 3 to 5 times before each dose. Do not shake this product. Measure the medicine with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.
When do you use linezolid?
Linezolid is an antibiotic used to treat certain serious bacterial infections. It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).
When should you not use linezolid?
1.0 Linezolid should not be used for empiric therapy, except under unusual circumstances, or to treat mild gram-positive infections where other antimicrobial agents would be effective. 1.0 Linezolid is contraindicated in any person with a known hypersensitivity to linezolid or any of the product components.