How do cytoplasmic determinants affect cell differentiation?
Cytoplasmic determinants are a type of substances found in the female gametes; they are responsible for the regulation of gene expression in the early development of the embryo. They lead to the differential specialization of blastomere during cleavage.
What do cytoplasmic determinants determine?
Cytoplasmic determinants are special molecules which play a very important role during oocyte maturation, in the female’s ovary. During this period of time, some regions of the cytoplasm accumulate some of these cytoplasmic determinants, whose distribution is thus very heterogenic.
What causes asymmetric cell division?
Asymmetric cell division (ACD) is a fundamental process whereby the asymmetric inheritance of cellular components (e.g. proteins, RNAs) during mitosis defines distinct fates for each daughter cell. This evolutionarily conserved division mode is used by stem and progenitor cells in different tissues.
What are some examples of cytoplasmic determinants?
- Germ Cell.
Are cytoplasmic determinants transcription factors?
Cytoplasmic determinants Indeed asymmetric distribution of cytoplasmic regulatory factors necessary for specification (e.g. mRNAs and proteins such as transcription factors) can influence the fate of the daughter cells.
What sort of specification is caused by cytoplasmic determinants?
Cytoplasmic determinants provide the necessary information for specifying embryonic cell fates. When inheritance of cytoplasmic determinants by a cell is sufficient for that cell to undergo its final differentiation, it is said to undergo autonomous cell fate specification.
What is the difference between asymmetric and symmetric cell division?
The key difference between symmetric and asymmetric stem cell division is that symmetric stem cell division produces two differentiated cells or two stem cells with equal cell fates while asymmetric stem cell division produces one stem and one non-stem daughter cell, which have different fates.
What does asymmetric cell division do?
An asymmetric cell division produces two daughter cells with different cellular fates. This is in contrast to symmetric cell divisions which give rise to daughter cells of equivalent fates.
What is the role of cytoplasmic determinants in differential gene expression?
This is because the egg cytoplasm is full of cytoplasmic determinants, molecules that impact gene expression. Since these are distributed unevenly throughout the zygote, each blastomere has a different collection of cytoplasmic determinants, which impact the genes in the cell differently.
What is a cytoplasmic determinant quizlet?
So cytoplasmic determinants are maternal substances that influence early development. When zygote undergoes mitosis, daughter cells contain different cytoplasmic determinants, leading to differential gene expression. Induction.
What are cytoplasmic determinants and inductive signals?
This process is generated by molecules that tell other cells to change their fate, called inductive signals. So, while determinants come from within the cell, inductive signals are passed from one cell into another and change the genes being activated and silenced.